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Details

Stereochemistry ACHIRAL
Molecular Formula C13H16N2S2
Molecular Weight 264.41
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-CYCLOHEXYL-2-BENZOTHIAZOSULFENAMIDE

SMILES

C1CCC(CC1)NSC2=NC3=C(S2)C=CC=C3

InChI

InChIKey=DEQZTKGFXNUBJL-UHFFFAOYSA-N
InChI=1S/C13H16N2S2/c1-2-6-10(7-3-1)15-17-13-14-11-8-4-5-9-12(11)16-13/h4-5,8-10,15H,1-3,6-7H2

HIDE SMILES / InChI

Description

N-cyclohexyl-2-benzothiazosulfenamide (Sulfenax® CBS) is used in rubber industry in processing of natural and synthetic rubber in rubber compounds as a fast accelerator of vulcanization with delayed action. N-cyclohexyl-2-benzothiazosulfenamide is a chemical allergen. It is used for diagnosis of contact allergy. It is a component of Mercapto Mix, used in the epicutaneous patch test, called T.R.U.E. TEST, approved by FDA in 1994. T.R.U.E. TEST is indicated for use as an aid in the diagnosis of allergic contact dermatitis in persons 18 years of age and older whose history suggests sensitivity to one or more of the 35 substances included on the T.R.U.E. TEST panels.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
T.R.U.E. TEST

PubMed

Sample Use Guides

In Vivo Use Guide
Apply the three adhesive panels of allergens and allergen mixes on healthy skin of the back. Remove panels and evaluate the skin 48 hours after application. Re-evaluate the skin 72 to 96 hours after application.
Route of Administration: Topical
In Vitro Use Guide
10 uM of N-cyclohexyl-2-benzothiazosulfenamide induced AhR-dependent gene expression in mouse hepatoma (H1L6.1c2) cells